Chimeric Peptide Beacons: a Direct Polypeptide Analog of DNA Molecular Beacons

Overview

Journal Chem Commun (Camb)

Publisher Royal Society of Chemistry

Specialty Chemistry

Date 2008 Mar 26

PMID 18361352

Citations 11

Authors

Kenneth J Oh

Kevin J Cash

Arica A Lubin

Kevin W Plaxco

Affiliations

Soon will be listed here.

Abstract

We have developed a new biosensor architecture, which is comprised of a polypeptide-peptide nucleic acid tri-block copolymer and which we have termed chimeric peptide beacons (CPB), that generates an optical output via a mechanism analogous to that employed in DNA-based molecular beacons.

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