Preimplantation Genetic Screening: "established" and Ready for Prime Time?

Overview

Journal Fertil Steril

Specialty Reproductive Medicine

Date 2008 Mar 21

PMID 18353323

Citations 16

Authors

Norbert Gleicher

Andrea Weghofer

David Barad

Affiliations

Soon will be listed here.

Abstract

Unless attempts to improve pregnancy rates and/or diminish miscarriage rates through preimplantation genetic screening (PGS) are applied to only carefully selected patients, they will fail. Because specific PGS indications have remained undefined, PGS should be considered an experimental procedure.

Citing Articles

An additive opinion to the committee opinion of ASRM and SART on the use of preimplantation genetic testing for aneuploidy (PGT-A).

Gleicher N, Barad D, Patrizio P, Gayete-Lafuente S, Gayete-Lafuente S, Weghofer A J Assist Reprod Genet. 2024; 42(1):71-80.

PMID: 39693036 PMC: 11805733. DOI: 10.1007/s10815-024-03318-z.

Time associations between U.S. birth rates and add-Ons to IVF practice between 2005-2016.

Gleicher N, Mochizuki L, Barad D Reprod Biol Endocrinol. 2021; 19(1):110.

PMID: 34256798 PMC: 8278617. DOI: 10.1186/s12958-021-00793-2.

The PGS/PGT-A controversy in IVF addressed as a formal conflict resolution analysis.

Mochizuki L, Gleicher N J Assist Reprod Genet. 2020; 37(3):677-687.

PMID: 32219600 PMC: 7125270. DOI: 10.1007/s10815-020-01688-8.

Preimplantation Genetic Testing for Breast Cancer.

Oribamise E, Ashiru O, Iloabachie E, Osumah J, Moruf O Niger Med J. 2019; 60(3):99-105.

PMID: 31543559 PMC: 6737793. DOI: 10.4103/nmj.NMJ_124_18.

A single trophectoderm biopsy at blastocyst stage is mathematically unable to determine embryo ploidy accurately enough for clinical use.

Gleicher N, Metzger J, Croft G, Kushnir V, Albertini D, Barad D Reprod Biol Endocrinol. 2017; 15(1):33.

PMID: 28449669 PMC: 5408377. DOI: 10.1186/s12958-017-0251-8.