Nocturnal Sleep in Huntington's Disease

Overview

Journal J Neurol

Specialty Neurology

Date 1991 Jul 1

PMID 1832711

Citations 47

Authors

M Wiegand

A A Moller

C J Lauer

S Stolz

W Schreiber

M Dose

J C Krieg

Affiliations

Soon will be listed here.

Abstract

Nocturnal sleep was studied in 16 inpatients with Huntington's disease. In comparison with healthy controls, patients exhibited a disturbed sleep pattern with increased sleep onset latency, reduced sleep efficiency, frequent nocturnal awakenings, more time spent awake and less slow wave sleep. These abnormalities correlated in part with duration of illness, severity of clinical symptoms, and degree of atrophy of the caudate nucleus. Patients showed an increased density of sleep spindles.

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