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Roles of Interleukin-1 and Tumor Necrosis Factor in Lipopolysaccharide-induced Hypoglycemia

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Journal Infect Immun
Date 1991 Jul 1
PMID 1828792
Citations 18
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Abstract

In this study, hypoglycemia induced by injection of lipopolysaccharide (LPS) or the recombinant cytokine interleukin-1 alpha or tumor necrosis factor alpha (administered alone or in combination) was compared. LPS-induced hypoglycemia was reversed significantly by recombinant interleukin-1 receptor antagonist.

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References
1.
NORTH R, Havell E . The antitumor function of tumor necrosis factor (TNF) II. Analysis of the role of endogenous TNF in endotoxin-induced hemorrhagic necrosis and regression of an established sarcoma. J Exp Med. 1988; 167(3):1086-99. PMC: 2188903. DOI: 10.1084/jem.167.3.1086. View

2.
Vogel S, Kaufman E, Tate M, Neta R . Recombinant interleukin-1 alpha and recombinant tumor necrosis factor alpha synergize in vivo to induce early endotoxin tolerance and associated hematopoietic changes. Infect Immun. 1988; 56(10):2650-7. PMC: 259625. DOI: 10.1128/iai.56.10.2650-2657.1988. View

3.
Del Rey A, Besedovsky H . Interleukin 1 affects glucose homeostasis. Am J Physiol. 1987; 253(5 Pt 2):R794-8. DOI: 10.1152/ajpregu.1987.253.5.R794. View

4.
Vogel S, Douches S, Kaufman E, Neta R . Induction of colony stimulating factor in vivo by recombinant interleukin 1 alpha and recombinant tumor necrosis factor alpha 1. J Immunol. 1987; 138(7):2143-8. View

5.
Dinarello C, Cannon J, Wolff S, Bernheim H, Beutler B, Cerami A . Tumor necrosis factor (cachectin) is an endogenous pyrogen and induces production of interleukin 1. J Exp Med. 1986; 163(6):1433-50. PMC: 2188124. DOI: 10.1084/jem.163.6.1433. View