Pseudohyperaldosteronism, Liquorice, and Hypertension

Overview

Journal J Clin Hypertens (Greenwich)

Specialty Cardiology & Vascular Diseases

Date 2008 Feb 8

PMID 18256580

Citations 22

Authors

Bruno Sontia

Jan Mooney

Lise Gaudet

Rhian M Touyz

Affiliations

Soon will be listed here.

Abstract

Consumption of large quantities of liquorice can cause hypokalemia and hypertension. These effects are associated with increased cortisol-mediated activation of renal mineralocorticoid receptors and hypoaldosteronism. The authors describe a patient with long-standing hypokalemia and uncontrolled hypertension related to excessive ingestion of liquorice. The case highlights the importance of obtaining a detailed dietary history, especially considering the increasing use of liquorice-containing foods, teas, and herbal products. The authors also discuss secondary causes of hypertension, focusing on pseudohyperaldosteronism.

Citing Articles

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Licorice Toxicity Presenting As Refractory Hypokalemia and Hypertension in an Elderly Patient.

Albahlawan R, Alafifi M, Ambrose Fistus V Cureus. 2024; 16(11):e72975.

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Primary hyperoxaluria: a case series.

Rather J, Rasheed R, Wani M, Bhat M, Wani I J Med Case Rep. 2023; 17(1):421.

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Liquorice Toxicity: A Comprehensive Narrative Review.

Ceccuzzi G, Rapino A, Perna B, Costanzini A, Farinelli A, Fiorica I Nutrients. 2023; 15(18).

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