Treatment of Rabbit Cheyletiellosis with Selamectin or Ivermectin: a Retrospective Case Study

Overview

Journal Acta Vet Scand

Publisher Biomed Central

Specialty Veterinary Medicine

Date 2008 Jan 4

PMID 18171479

Citations 17

Authors

Marianne Mellgren

Kerstin Bergvall

Affiliations

Soon will be listed here.

Abstract

Background: A retrospective study of rabbits treated against cheyletiellosis was performed to evaluate the efficacy and safety of selamectin or ivermectin in clinical practice.

Methods: Medical records from 53 rabbits with microscopically confirmed Cheyletiella infestation were collected from two small animal clinics. The rabbits were divided into three groups, based on treatment protocols. Group 1 included 11 rabbits treated with ivermectin injections at 200-476 microg kg-1 subcutaneously 2-3 times, with a mean interval of 11 days. In Group 2, 27 rabbits were treated with a combination of subcutaneous ivermectin injections (range 618-2185 microgkg-1) and oral ivermectin (range 616-2732 microgkg-1) administered by the owners, 3-6 times at 10 days interval. The last group (Group 3) included 15 rabbits treated with selamectin spot-on applications of 6.2-20,0 mgkg-1, 1-3 times with an interval of 2-4 weeks. Follow-up time was 4 months-4.5 years.

Results: Rabbits in remission were 9/11 (81,8%), 14/27 (51,9%) and 12/15 (80,8%) in groups 1, 2 and 3, respectively.

Conclusion: All treatment protocols seemed to be sufficiently effective and safe for practice use. Though very high doses were used in Group 2 (ivermectin injections followed by oral administration), the protocol seemed less efficacious compared to ivermectin injections (Group 1) and selamectin spot on (Group 3), respectively, although not statistically significant. Controlled prospective studies including larger groups are needed to further evaluate efficacy of the treatment protocols.

Citing Articles

Farm Animal Welfare during Transport and at the Slaughterhouse: Perceptions of Slaughterhouse Employees, Livestock Drivers, and Veterinarians.

Lipovsek M, Kirbis A, Tomazic I, Dovc A, Krizman M Animals (Basel). 2024; 14(3).

PMID: 38338086 PMC: 10854723. DOI: 10.3390/ani14030443.

Cats' and dogs' welfare: text mining and topics modeling analysis of the scientific literature.

Adamakopoulou C, Benedetti B, Zappaterra M, Felici M, Masebo N, Previti A Front Vet Sci. 2023; 10:1268821.

PMID: 37901113 PMC: 10601470. DOI: 10.3389/fvets.2023.1268821.

Organic Milk Production and Dairy Farming Constraints and Prospects under the Laws of the European Union.

Grodkowski G, Golebiewski M, Slosarz J, Grodkowska K, Kostusiak P, Sakowski T Animals (Basel). 2023; 13(9).

PMID: 37174494 PMC: 10177354. DOI: 10.3390/ani13091457.

Main mites associated with dermatopathies present in dogs and other members of the Canidae family.

Thomson P, Carreno N, Nunez A Open Vet J. 2023; 13(2):131-142.

PMID: 37073249 PMC: 10105784. DOI: 10.5455/OVJ.2023.v13.i2.1.

The Social Construction of Narratives and Arguments in Animal Welfare Discourse and Debate.

Muhammad M, Stokes J, Morgans L, Manning L Animals (Basel). 2022; 12(19).

PMID: 36230322 PMC: 9559530. DOI: 10.3390/ani12192582.

References

Bowman D, Fogelson M, Carbone L . Effect of ivermectin on the control of ear mites (Psoroptes cuniculi) in naturally infested rabbits. Am J Vet Res. 1992; 53(1):105-9. View

Cutler S . Ectopic Psoroptes cuniculi infestation in a pet rabbit. J Small Anim Pract. 1998; 39(2):86-7. DOI: 10.1111/j.1748-5827.1998.tb03599.x. View

McKellar Q, Midgley D, Galbraith E, Scott E, Bradley A . Clinical and pharmacological properties of ivermectin in rabbits and guinea pigs. Vet Rec. 1992; 130(4):71-3. DOI: 10.1136/vr.130.4.71. View

UHLIR J . Humoral and cellular immune response of rabbits to Psoroptes cuniculi, the rabbit scab mite. Vet Parasitol. 1991; 40(3-4):325-34. DOI: 10.1016/0304-4017(91)90112-9. View

Ulutas B, Voyvoda H, Bayramli G, Karagenc T . Efficacy of topical administration of eprinomectin for treatment of ear mite infestation in six rabbits. Vet Dermatol. 2005; 16(5):334-7. DOI: 10.1111/j.1365-3164.2005.00464.x. View

Chadwick A . Use of a 0.25 per cent fipronil pump spray formulation to treat canine cheyletiellosis. J Small Anim Pract. 1997; 38(6):261-2. DOI: 10.1111/j.1748-5827.1997.tb03364.x. View

Paradis M, Villeneuve A . Efficacy of Ivermectin against Cheyletiella yasguri Infestation in Dogs. Can Vet J. 1988; 29(8):633-5. PMC: 1680781. View

Scarampella F, Pollmeier M, Visser M, Boeckh A, Jeannin P . Efficacy of fipronil in the treatment of feline cheyletiellosis. Vet Parasitol. 2005; 129(3-4):333-9. DOI: 10.1016/j.vetpar.2005.02.008. View

Page N, de Jaham C, Paradis M . Observations on topical ivermectin in the treatment of otoacariosis, cheyletiellosis, and toxocariosis in cats. Can Vet J. 2000; 41(10):773-6. PMC: 1476370. View

10.

McTier T, Hair J, Walstrom D, Thompson L . Efficacy and safety of topical administration of selamectin for treatment of ear mite infestation in rabbits. J Am Vet Med Assoc. 2003; 223(3):322-4. DOI: 10.2460/javma.2003.223.322. View

11.

Kurtdede A, Karaer Z, Acar A, Guzel M, Cingi C, Ural K . Use of selamectin for the treatment of psoroptic and sarcoptic mite infestation in rabbits. Vet Dermatol. 2007; 18(1):18-22. DOI: 10.1111/j.1365-3164.2007.00563.x. View

12.

Bishop B, Bruce C, Evans N, Goudie A, Gration K, Gibson S . Selamectin: a novel broad-spectrum endectocide for dogs and cats. Vet Parasitol. 2000; 91(3-4):163-76. DOI: 10.1016/s0304-4017(00)00289-2. View

13.

Mueller R, Bettenay S . Efficacy of selamectin in the treatment of canine cheyletiellosis. Vet Rec. 2003; 151(25):773. View

14.

Curtis C . Current trends in the treatment of Sarcoptes, Cheyletiella and Otodectes mite infestations in dogs and cats. Vet Dermatol. 2004; 15(2):108-14. DOI: 10.1111/j.1365-3164.2004.00362.x. View

15.

Voyvoda H, Ulutas B, Eren H, Karagenc T, Bayramli G . Use of doramectin for treatment of sarcoptic mange in five Angora rabbits. Vet Dermatol. 2005; 16(4):285-8. DOI: 10.1111/j.1365-3164.2005.00446.x. View

16.

Wagner R, Wendlberger U . Field efficacy of moxidectin in dogs and rabbits naturally infested with Sarcoptes spp., Demodex spp. and Psoroptes spp. mites. Vet Parasitol. 2000; 93(2):149-58. DOI: 10.1016/s0304-4017(00)00357-5. View

17.

Chailleux N, Paradis M . Efficacy of selamectin in the treatment of naturally acquired cheyletiellosis in cats. Can Vet J. 2002; 43(10):767-70. PMC: 339606. View