Properties of Blast Cells in 'control' Cultures of Human Blood Lymphocytes. Preliminary Note

Overview

Journal Clin Exp Immunol

Publisher Oxford University Press

Specialty Allergy & Immunology

Date 1976 Apr 1

PMID 181188

Citations 2

Authors

P FARNES

P E HARRISON

B E Barker

Affiliations

Soon will be listed here.

Abstract

Ficoll-Hypaque separated normal human peripheral blood lymphocytes undergo appreciable blastogenesis in RPMI 1640-pooled human serum or - autologous plasma. During the 1st week, granulated blasts with peroixdase activity and ultrastructural properties of granulocytes precursors appear. These cells, which appear to be relateed to CFC (colony-forming cells), contribute to the mitotic population in these unstimulated "control" cultures prior to 6 days.

Citing Articles

DNA-synthesizing cells in the blood in coeliac disease and inflammatory bowel disease.

Holmes G, Bratt P, LING N, COOKE W Clin Exp Immunol. 1977; 28(3):484-9.

PMID: 891023 PMC: 1541016.

Spontaneous lymphocyte transformation in chronic lymphocytic leukaemia.

Semenzato G, Amadori G, Tosato F, Gasparotto G Clin Exp Immunol. 1977; 28(3):542-5.

PMID: 302167 PMC: 1541010.

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