Effects of Manganese on Streptococcus Mutans Planktonic and Biofilm Growth

Overview

Journal Caries Res

Specialty Dentistry

Date 2007 Nov 10

PMID 17992012

Citations 7

Authors

P Arirachakaran

S Luengpailin

J A Banas

J E Mazurkiewicz

E Benjavongkulchai

Affiliations

Soon will be listed here.

Abstract

Streptococcus mutans, an agent of dental caries, was tested for growth in the presence or absence of manganese (Mn), since studies have linked Mn levels with cariogenic potential. Seven S. mutans serotype c strains were grown in chemically defined medium under different atmospheric conditions: 5% CO2, O2-enriched 5% CO2 (shaking) and anaerobic. There was significant strain variability with respect to Mn requirements under the various conditions tested. Both sucrose-dependent and sucrose-independent biofilm growth by strain UA159 were affected by the absence of Mn. S. mutans strains show highly variable responses to both high and low Mn concentrations.

Citing Articles

Manganese Uptake, Mediated by SloABC and MntH, Is Essential for the Fitness of Streptococcus mutans.

Kajfasz J, Katrak C, Ganguly T, Vargas J, Wright L, Peters Z mSphere. 2020; 5(1).

PMID: 31915219 PMC: 6952196. DOI: 10.1128/mSphere.00764-19.

Experimental Models of Oral Biofilms Developed on Inert Substrates: A Review of the Literature.

Darrene L, Cecile B Biomed Res Int. 2016; 2016:7461047.

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Discrete Responses to Limitation for Iron and Manganese in Agrobacterium tumefaciens: Influence on Attachment and Biofilm Formation.

Heindl J, Hibbing M, Xu J, Natarajan R, Buechlein A, Fuqua C J Bacteriol. 2015; 198(5):816-29.

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In vitro manganese-dependent cross-talk between Streptococcus mutans VicK and GcrR: implications for overlapping stress response pathways.

Downey J, Mashburn-Warren L, Ayala E, Senadheera D, Hendrickson W, McCall L PLoS One. 2014; 9(12):e115975.

PMID: 25536343 PMC: 4275253. DOI: 10.1371/journal.pone.0115975.

PerR-regulated manganese ion uptake contributes to oxidative stress defense in an oral streptococcus.

Wang X, Tong H, Dong X Appl Environ Microbiol. 2014; 80(8):2351-9.

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