Functional Membrane Diffusion of G-protein Coupled Receptors

Overview

Journal Eur Biophys J

Specialty Biophysics

Date 2007 Sep 28

PMID 17899063

Citations 15

Authors

Aurelie Baker

Aude Sauliere

Fabrice Dumas

Claire Millot

Serge Mazeres

Andre Lopez

Laurence Salome

Affiliations

Soon will be listed here.

Abstract

G-protein-coupled receptor function involves interactions between the receptor, G-proteins and effectors in the cell plasma membrane. The main biochemical processes have been individually identified but the mechanisms governing the successive protein-protein interactions of this complex multi-molecular machinery have yet to be established. We discuss advances in understanding the functional dynamics of the receptor resulting from diffusion measurements, and in the context of the plasma membrane organization.

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