» Articles » PMID: 17884492

Rynaxypyr: a New Insecticidal Anthranilic Diamide That Acts As a Potent and Selective Ryanodine Receptor Activator

Abstract

Rynaxypyr is a highly potent and selective activator of insect ryanodine receptors with exceptional activity on a broad range of Lepidoptera. A strong correlation between insecticidal activity and ryanodine receptor activation is observed along with selective activity against insect over mammalian receptors. The synthesis and biological results are presented.

Citing Articles

Residual Dynamics of Chlorantraniliprole and Fludioxonil in Soil and Their Effects on the Microbiome.

Hao N, Zhang H, Jia H, Zhao Y, Li J, Feng X J Xenobiot. 2025; 15(1).

PMID: 39846536 PMC: 11840292. DOI: 10.3390/jox15010004.


Transcriptome profiling reveals novel insights into the regulation of calcium ion and detoxification genes driving chlorantraniliprole resistance in .

Han C, Kim J Heliyon. 2024; 10(23):e40556.

PMID: 39660196 PMC: 11629198. DOI: 10.1016/j.heliyon.2024.e40556.


Cardiotoxicity of the diamide insecticide chlorantraniliprole in the intact heart and in isolated cardiomyocytes from the honey bee.

Kaabeche M, Charreton M, Kadala A, Mutterer J, Charnet P, Collet C Sci Rep. 2024; 14(1):14938.

PMID: 38942905 PMC: 11213956. DOI: 10.1038/s41598-024-65007-2.


Synthesis and Insecticidal Activity of Novel Anthranilic Diamide Insecticides Containing Indane and Its Analogs.

Yang Z, Hu R, Chen J, Du X Int J Mol Sci. 2024; 25(4).

PMID: 38397120 PMC: 10889706. DOI: 10.3390/ijms25042445.


Characterization of the inheritance of field-evolved resistance to diamides in the fall armyworm (Spodoptera frugiperda) (Lepidoptera: Noctuidae) population from Puerto Rico.

Posos-Parra O, Mota-Sanchez D, Pittendrigh B, Wise J, DiFonzo C, Patterson E PLoS One. 2024; 19(2):e0295928.

PMID: 38394153 PMC: 10889863. DOI: 10.1371/journal.pone.0295928.