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The Function of Dmrt Genes in Vertebrate Development: It is Not Just About Sex

Overview
Journal Dev Biol
Publisher Elsevier
Date 2007 Aug 28
PMID 17720152
Citations 47
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Abstract

The Dmrt genes encode a large family of transcription factors whose function in sexual development has been well studied in invertebrates and vertebrates. Their expression pattern is not restricted to the developing gonads, indicating that Dmrt genes might regulate other developmental processes. Here we review the expression pattern of several members of this family across species and summarize recent findings on the function of a subset of these genes in non-gonadal tissues.

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