Longitudinal Changes in Corneal Irregular Astigmatism and Visual Acuity in Eyes with Keratoconus

Overview

Journal Jpn J Ophthalmol

Specialty Ophthalmology

Date 2007 Jul 31

PMID 17660986

Citations 15

Authors

Mariko Suzuki

Shiro Amano

Norihiko Honda

Tomohiko Usui

Satoru Yamagami

Tetsuro Oshika

Affiliations

Soon will be listed here.

Abstract

Purpose: To quantitatively investigate the time course of changes in corneal irregular astigmatism and their relation to best spectacle-corrected visual acuity (BSCVA) in eyes with keratoconus.

Methods: Subjects were 47 patients (57 eyes) with keratoconus who had undergone videokeratography examinations at least twice, with an interval of 1 year or longer between each examination. By means of Fourier series harmonic analysis, topography data were separated into spherical component, regular astigmatism, asymmetry, and higher order irregularity.

Results: In eyes that showed apparent progression on color-coded maps, the yearly rate of change was significantly positive for spherical component (P = 0.03) and higher order irregularity (P = 0.006). In eyes with apparent progression, the yearly change rate of BSCVA was significantly positive (P = 0.001), but not in the eyes without apparent progression (P = 0.1655). In eyes with progression on maps, the yearly change rate of BSCVA was significantly correlated with the change rate of higher order irregularity per year (r = 0.770, P = 0.0004).

Conclusions: The results indicated that progression of keratoconus is associated with deterioration of BSCVA, which is in turn significantly correlated with increases in corneal higher order irregularity.

Citing Articles

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Regular and irregular astigmatism of bullous keratopathy using Fourier harmonic analysis with anterior segment optical coherence tomography.

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Impact of rigid gas-permeable contact lens on keratometric indices and corneal thickness of keratoconus eyes examined with anterior segment optical coherence tomography.

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PMID: 35802557 PMC: 9269451. DOI: 10.1371/journal.pone.0270519.

Corneal topography in keratoconus evaluated more than 30 years after penetrating keratoplasty: a Fourier harmonic analysis.

Ono T, Kawasaki Y, Chen L, Toyono T, Shirakawa R, Yoshida J Sci Rep. 2020; 10(1):14880.

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References

Olsen T, Bek T, Hjortdal J . Evaluating surgically induced astigmatism by Fourier analysis of corneal topography data. J Cataract Refract Surg. 1996; 22(3):318-23. DOI: 10.1016/s0886-3350(96)80243-4. View

Rabinowitz Y . Keratoconus. Surv Ophthalmol. 1998; 42(4):297-319. DOI: 10.1016/s0039-6257(97)00119-7. View

Oshika T, Tanabe T, Tomidokoro A, Amano S . Progression of keratoconus assessed by fourier analysis of videokeratography data. Ophthalmology. 2002; 109(2):339-42. DOI: 10.1016/s0161-6420(01)00903-4. View

Smolek M, Klyce S, Maeda N . Keratoconus and contact lens-induced corneal warpage analysis using the keratomorphic diagram. Invest Ophthalmol Vis Sci. 1994; 35(13):4192-204. View

Raasch T . Corneal topography and irregular astigmatism. Optom Vis Sci. 1995; 72(11):809-15. DOI: 10.1097/00006324-199511000-00006. View