In Vivo Activity of a Novel Polymeric Guanidine in Experimental Skin Infection with Methicillin-resistant Staphylococcus Aureus

Overview

Journal Antimicrob Agents Chemother

Publisher American Society for Microbiology

Specialty Pharmacology

Date 2007 Jul 11

PMID 17620381

Citations 3

Authors

Christina Kratzer

Selma Tobudic

Karin Macfelda

Wolfgang Graninger

Apostolos Georgopoulos

Affiliations

Soon will be listed here.

Abstract

The in vivo efficacy of the novel polymeric guanidine AKACID Plus was evaluated in a guinea pig model of experimental skin infection with methicillin-resistant Staphylococcus aureus (MRSA). Topical application of AKACID Plus at concentrations of > or =0.5% was as effective as mupirocin 2% cream in the treatment of superficial skin infection with MRSA.

Citing Articles

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Akacid medical formulation induces apoptosis in myeloid and lymphatic leukemic cell lines in vitro and in vivo.

Neuwirt H, Wabnig E, Feistritzer C, Eder I, Salvador C, Puhr M PLoS One. 2015; 10(2):e0117806.

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