Recent Advances in Eosinophil Biology

Overview

Journal Int Arch Allergy Immunol

Specialty Allergy & Immunology

Date 2007 Aug 9

PMID 17541270

Citations 20

Authors

Simon P Hogan

Affiliations

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Abstract

Eosinophils are pleiotropic multi-functional leukocytes involved in initiation and propagation of diverse inflammatory responses. Recent studies examining eosinophil biology have focused on delineating the molecular basis of FIP1L1/PDGRFalpha-fusion gene induced HES, the molecular steps involved in eosinophil recruitment in tumor-associated eosinophilia and EGID, and the role of eosinophils in asthma. In this review, these studies are summarized, focusing on the implications of these findings in the understanding the role of eosinophils in diseases.

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