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Interleukin-12: a Master Regulator

Overview
Journal J Exp Med
Date 2007 May 9
PMID 17485522
Citations 7
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Abstract

Early resistance to pathogens requires a swift response from NK cells. In 1989, Giorgio Trinchieri identified an NK growth factor and activator, later called interleukin-12 (IL-12). This discovery helped reveal the regulatory link between innate and adaptive immunity.

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