» Articles » PMID: 17329630

Combination of Neuronal Signals Representing Object-centered Location and Saccade Direction in Macaque Supplementary Eye Field

Overview
Journal J Neurophysiol
Specialties Neurology
Physiology
Date 2007 Mar 3
PMID 17329630
Citations 5
Authors
Affiliations
Soon will be listed here.
Abstract

Neurons in the macaque supplementary eye field (SEF) fire at different rates in conjunction with planning saccades in different directions. They also exhibit object-centered spatial selectivity, firing at different rates when the target of the saccade is at the left or right end of a horizontal bar. To compare the rate of incidence of the two kinds of signal, and to determine how they combine, we recorded from SEF neurons while monkeys performed a task in which the target (a dot or the left or right end of a horizontal bar) could appear in any visual field quadrant. During the period when the target was visible on the screen and the monkey was preparing to make a saccade, many neurons exhibited selectivity for saccade direction, firing at a rate determined by the direction of the impending saccade irrespective of whether the target was a dot or the end of a bar. On bar trials, many of the same neurons exhibited object-centered selectivity, firing more strongly when the target was at the preferred end of the bar regardless of saccade direction. The rate of incidence of object-centered selectivity (33%) was lower overall than that of saccade-direction selectivity (56%). Signals related to saccade direction and the object-centered location of the target tended to combine additively. The results suggest that the SEF is at a transitional stage between representing the object-centered command and specifying the parameters of the saccade.

Citing Articles

Thinking in spatial terms: decoupling spatial representation from sensorimotor control in monkey posterior parietal areas 7a and LIP.

Chafee M, Crowe D Front Integr Neurosci. 2013; 6:112.

PMID: 23355813 PMC: 3555036. DOI: 10.3389/fnint.2012.00112.


Supplementary eye field encodes option and action value for saccades with variable reward.

So N, Stuphorn V J Neurophysiol. 2010; 104(5):2634-53.

PMID: 20739596 PMC: 4073903. DOI: 10.1152/jn.00430.2010.


Role of supplementary eye field in saccade initiation: executive, not direct, control.

Stuphorn V, Brown J, Schall J J Neurophysiol. 2009; 103(2):801-16.

PMID: 19939963 PMC: 2822692. DOI: 10.1152/jn.00221.2009.


Transformation of a virtual action plan into a motor plan in the premotor cortex.

Nakayama Y, Yamagata T, Tanji J, Hoshi E J Neurosci. 2008; 28(41):10287-97.

PMID: 18842888 PMC: 6671018. DOI: 10.1523/JNEUROSCI.2372-08.2008.


Neural ensemble decoding reveals a correlate of viewer- to object-centered spatial transformation in monkey parietal cortex.

Crowe D, Averbeck B, Chafee M J Neurosci. 2008; 28(20):5218-28.

PMID: 18480278 PMC: 3844802. DOI: 10.1523/JNEUROSCI.5105-07.2008.