The Potential Role of Podoplanin in Tumour Invasion

Overview

Journal Br J Cancer

Specialty Oncology

Date 2006 Dec 21

PMID 17179989

Citations 122

Authors

A Wicki

G Christofori

Affiliations

Soon will be listed here.

Abstract

Podoplanin is a small mucin-like transmembrane protein, widely expressed in various specialised cell types throughout the body. Here, we revisit the mechanism of podoplanin-mediated tumour invasion. We compare molecular pathways leading to single and collective cell invasion and discuss novel distinct concepts of tumour cell invasion.

Citing Articles

Role of Podoplanin (PDPN) in Advancing the Progression and Metastasis of Glioblastoma Multiforme (GBM).

Sharma B, Agriantonis G, Shafaee Z, Twelker K, Bhatia N, Kuschner Z Cancers (Basel). 2024; 16(23).

PMID: 39682237 PMC: 11639870. DOI: 10.3390/cancers16234051.

Combining RNAscope, Immunohistochemistry (IHC) and Digital Image Analysis to Assess Podoplanin (PDPN) Protein and PDPN_mRNA Expression on Formalin-Fixed Paraffin-Embedded Normal Human Placenta Tissues.

Tomescu L, Cosma A, Pasca Fenesan M, Melnic E, Petrovici V, Sarb S Curr Issues Mol Biol. 2024; 46(6):5161-5177.

PMID: 38920982 PMC: 11202497. DOI: 10.3390/cimb46060310.

Prognostic significance of tumor budding in patients with pancreatic invasive ductal carcinoma who received neoadjuvant therapy.

Ibuki E, Kadota K, Kimura N, Ishikawa R, Oshima M, Okano K Heliyon. 2024; 10(1):e23928.

PMID: 38205326 PMC: 10777074. DOI: 10.1016/j.heliyon.2023.e23928.

Exploring the clinical utility of angioinvasion markers in papillary thyroid cancer: a literature review.

Buczynska A, Kosciuszko M, Kretowski A, Poplawska-Kita A Front Endocrinol (Lausanne). 2023; 14:1261860.

PMID: 38089632 PMC: 10711683. DOI: 10.3389/fendo.2023.1261860.

What is new in cancer-associated fibroblast biomarkers?.

Zhao Z, Li T, Yuan Y, Zhu Y Cell Commun Signal. 2023; 21(1):96.

PMID: 37143134 PMC: 10158035. DOI: 10.1186/s12964-023-01125-0.

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