Carbohydrate Antigens: Synthesis Aspects and Immunological Applications in Cancer
Overview
Affiliations
Tumor Associated Carbohydrate Antigens (TACAs) constitute powerful tools as tumor markers and as targets for anticancer immunotherapy. In this review, methods of production of glycopeptide-based vaccines, as well as results of preclinical and clinical studies in cancer patients are discussed.
Glycoconjugate Nanoparticle-Based Systems in Cancer Immunotherapy: Novel Designs and Recent Updates.
Barchi Jr J Front Immunol. 2022; 13:852147.
PMID: 35432351 PMC: 9006936. DOI: 10.3389/fimmu.2022.852147.
Chemical synthesis and immunological evaluation of entirely carbohydrate conjugate Globo H-PS A1.
Ghosh S, Trabbic K, Shi M, Nishat S, Eradi P, Kleski K Chem Sci. 2021; 11(48):13052-13059.
PMID: 34123241 PMC: 8163331. DOI: 10.1039/d0sc04595k.
Carbohydrate antigen delivery by water soluble copolymers as potential anti-cancer vaccines.
Qin Q, Yin Z, Bentley P, Huang X Medchemcomm. 2014; 5(8):1126-1129.
PMID: 25396038 PMC: 4225718. DOI: 10.1039/C4MD00103F.
Tobacco mosaic virus as a new carrier for tumor associated carbohydrate antigens.
Yin Z, Nguyen H, Chowdhury S, Bentley P, Bruckman M, Miermont A Bioconjug Chem. 2012; 23(8):1694-703.
PMID: 22812480 PMC: 3426870. DOI: 10.1021/bc300244a.
Recent Development in Carbohydrate Based Anti-cancer Vaccines.
Yin Z, Huang X J Carbohydr Chem. 2012; 31(3):143-186.
PMID: 22468019 PMC: 3312792. DOI: 10.1080/07328303.2012.659364.