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Claude Leclerc

Explore the profile of Claude Leclerc including associated specialties, affiliations and a list of published articles. Areas
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Articles 132
Citations 4257
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Recent Articles
1.
Molinari P, Crespo M, Molina G, Dho N, Marinho F, Maletto B, et al.
Immunology . 2022 Nov; 169(1):27-41. PMID: 36371679
Although the baculovirus Autographa californica multiple nuclear polyhedrosis virus (AcMNPV) infects lepidopteran invertebrates as natural hosts, represents an efficient vector for vaccine development. Baculovirus surface display induces strong humoral responses...
2.
Dadaglio G, Fayolle C, Oberkampf M, Tang A, Rudilla F, Couillin I, et al.
Oncoimmunology . 2020 Sep; 9(1):1758606. PMID: 32923117
Antitumor immunity is mediated by Th1 CD4 and CD8 T lymphocytes, which induce tumor-specific cytolysis, whereas Th17 CD4 T cells have been described to promote tumor growth. Here, we explored...
3.
Rosenbaum P, Artaud C, Bay S, Ganneau C, Campone M, Delaloge S, et al.
Cancer Immunol Immunother . 2020 Feb; 69(5):703-716. PMID: 32034426
Cancer is one of the main causes of mortality worldwide and a major public health concern. Among various strategies, therapeutic vaccines have been developed to stimulate anti-tumoral immune responses. However,...
4.
Cousin C, Oberkampf M, Felix T, Rosenbaum P, Weil R, Fabrega S, et al.
Cell Rep . 2019 Jan; 26(5):1242-1257.e7. PMID: 30699352
Lentiviruses are among the most promising viral vectors for in vivo gene delivery. To overcome the risk of insertional mutagenesis, integrase-deficient lentiviral vectors (IDLVs) have been developed. We show here...
5.
Szekely T, Roy O, Deriaud E, Job A, Lo-Man R, Leclerc C, et al.
J Med Chem . 2018 Oct; 61(21):9568-9582. PMID: 30351939
We present here for the first time the synthesis and immunological evaluation of a fully synthetic three-component anticancer vaccine candidate that consists of a β-glycotripeptoid core mimicking a cluster of...
6.
Oberkampf M, Guillerey C, Mouries J, Rosenbaum P, Fayolle C, Bobard A, et al.
Nat Commun . 2018 Jun; 9(1):2241. PMID: 29884826
Cross-presentation allows exogenous antigen presentation in association with major histocompatibility complex class I molecules, a process crucial for the priming of CD8 T-cell responses against viruses and tumors. By contrast...
7.
Terra M, Oberkampf M, Fayolle C, Rosenbaum P, Guillerey C, Dadaglio G, et al.
Cancer Res . 2018 Mar; 78(11):3014-3026. PMID: 29523540
A growing number of observations has suggested that plasmacytoid dendritic cells (pDC) play a critical role in tumor biology. In patients, infiltration of tumors by pDCs generally correlates with a...
8.
Chaoul N, Tang A, Desrues B, Oberkampf M, Fayolle C, Ladant D, et al.
Oncoimmunology . 2018 Feb; 7(3):e1404213. PMID: 29399403
Regulatory T-cells (Tregs) are crucial for the maintenance of immune tolerance and homeostasis as well as for preventing autoimmune diseases, but their impact on the survival of cancer patients remains...
9.
Rexhaj S, Leclerc C, Bonsack C, Golay P, Favrod J
Front Psychiatry . 2017 Oct; 8:178. PMID: 28983262
Objectives: This study aimed to assess the acceptability and feasibility of a new tailored intervention for informal caregivers: the (Together) program. Methods: An open pre-post within-subject comparison pilot study was...
10.
Bernelin-Cottet C, Deloizy C, Stanek O, Barc C, Bouguyon E, Urien C, et al.
Front Immunol . 2017 Jul; 8:831. PMID: 28740498
[This corrects the article on p. 641 in vol. 7, PMID: 28082980.].