Olfactory Receptor Gene Repertoires in Mammals

Overview

Journal Mutat Res

Publisher Elsevier

Specialty Genetics

Date 2006 Dec 15

PMID 17166524

Citations 19

Authors

Sylvie Rouquier

Dominique Giorgi

Affiliations

Soon will be listed here.

Abstract

In mammals, olfaction is mediated by two distinct organs that are located in the nasal cavity: the main olfactory epithelium (MOE) that binds volatile odorants is responsible for the conscious perception of odors, and the vomeronasal organ (VNO) that binds pheromones is responsible for various behavioral and neuroendocrine responses between individuals of a same species. Odorants and pheromones bind to seven transmembrane domain G-protein-coupled receptors that permit signal transduction. These receptors are encoded by large multigene families that evolved in mammal species in function of specific olfactory needs.

Citing Articles

Localized Expression of Olfactory Receptor Genes in the Olfactory Organ of Common Minke Whales.

Hirose A, Nakamura G, Nikaido M, Fujise Y, Kato H, Kishida T Int J Mol Sci. 2024; 25(7).

PMID: 38612665 PMC: 11012115. DOI: 10.3390/ijms25073855.

The Expansion of House Mouse Major Urinary Protein Genes Likely Did Not Facilitate Commensalism with Humans.

Macholan M, Daniszova K, Hiadlovska Z Genes (Basel). 2023; 14(11).

PMID: 38003032 PMC: 10671799. DOI: 10.3390/genes14112090.

Copy Number Variation Analysis Revealed the Evolutionary Difference between Chinese Indigenous Pigs and Asian Wild Boars.

Fan S, Kong C, Chen Y, Zheng X, Zhou R, Zhang X Genes (Basel). 2023; 14(2).

PMID: 36833399 PMC: 9957247. DOI: 10.3390/genes14020472.

The diet of early birds based on modern and fossil evidence and a new framework for its reconstruction.

Miller C, Pittman M Biol Rev Camb Philos Soc. 2021; 96(5):2058-2112.

PMID: 34240530 PMC: 8519158. DOI: 10.1111/brv.12743.

Discovery of Orphan Olfactory Receptor 6M1 as a New Anticancer Target in MCF-7 Cells by a Combination of Surface Plasmon Resonance-Based and Cell-Based Systems.

Choi Y, Shim J, Park J, Kim Y, Kim M Sensors (Basel). 2021; 21(10).

PMID: 34065710 PMC: 8156394. DOI: 10.3390/s21103468.