Thematic Review Series: Systems Biology Approaches to Metabolic and Cardiovascular Disorders. Proteomics Approaches to the Systems Biology of Cardiovascular Diseases

Overview

Journal J Lipid Res

Publisher Elsevier

Specialty Biochemistry

Date 2006 Oct 27

PMID 17065662

Citations 13

Authors

Thomas A Drake

Peipei Ping

Affiliations

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Abstract

Proteins play a central role in a systems view of biologic processes. This review provides an overview of proteomics from a systems perspective. We survey the key tools and methodologies used, present examples of how these are currently being used in the systems biology context, and discuss future directions.

Citing Articles

Integrated Transcriptome and Untargeted Metabolomic Analyses Revealed the Role of Methyltransferase Lae1 in the Regulation of Phospholipid Metabolism in .

Shen Y, Zhang Y, Zhang H, Wang X, Chen J, Li Y J Fungi (Basel). 2023; 9(1).

PMID: 36675941 PMC: 9864869. DOI: 10.3390/jof9010120.

Top-down Proteomics: Technology Advancements and Applications to Heart Diseases.

Cai W, Tucholski T, Gregorich Z, Ge Y Expert Rev Proteomics. 2016; 13(8):717-30.

PMID: 27448560 PMC: 5026638. DOI: 10.1080/14789450.2016.1209414.

Top-down proteomics in health and disease: challenges and opportunities.

Gregorich Z, Ge Y Proteomics. 2014; 14(10):1195-210.

PMID: 24723472 PMC: 4100610. DOI: 10.1002/pmic.201300432.

Proteomics in heart failure: top-down or bottom-up?.

Gregorich Z, Chang Y, Ge Y Pflugers Arch. 2014; 466(6):1199-209.

PMID: 24619480 PMC: 4037365. DOI: 10.1007/s00424-014-1471-9.

Endobiogeny: a global approach to systems biology (part 1 of 2).

Lapraz J, Hedayat K Glob Adv Health Med. 2014; 2(1):64-78.

PMID: 24381827 PMC: 3833585. DOI: 10.7453/gahmj.2013.2.1.011.