Introducing SONS, a Tool for Operational Taxonomic Unit-based Comparisons of Microbial Community Memberships and Structures

Overview

Journal Appl Environ Microbiol

Specialties Environmental Health
Microbiology

Date 2006 Oct 6

PMID 17021230

Citations 103

Authors

Patrick D Schloss

Jo Handelsman

Affiliations

Soon will be listed here.

Abstract

The recent advent of tools enabling statistical inferences to be drawn from comparisons of microbial communities has enabled the focus of microbial ecology to move from characterizing biodiversity to describing the distribution of that biodiversity. Although statistical tools have been developed to compare community structures across a phylogenetic tree, we lack tools to compare the memberships and structures of two communities at a particular operational taxonomic unit (OTU) definition. Furthermore, current tests of community structure do not indicate the similarity of the communities but only report the probability of a statistical hypothesis. Here we present a computer program, SONS, which implements nonparametric estimators for the fraction and richness of OTUs shared between two communities.

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