Mycobacterium Tuberculosis Complex and Mycobacterial Heat Shock Proteins in Lymph Node Tissue from Patients with Pulmonary Sarcoidosis

Overview

Journal J Clin Microbiol

Specialty Microbiology

Date 2006 Sep 7

PMID 16954298

Citations 48

Authors

Anna Dubaniewicz

Miroslawa Dubaniewicz-Wybieralska

Adam Sternau

Zofia Zwolska

Ewa Izycka-Swieszewska

Ewa Augustynowicz-Kopec

Jaroslaw Skokowski

Mahavir Singh

Lech Zimnoch

Affiliations

Soon will be listed here.

Abstract

We demonstrated that not whole Mycobacterium tuberculosis but its particular antigens, hsp70(Mtb), hsp65(Mtb), and hsp16(Mtb), are present in lymph node tissues of patients with sarcoidosis (SA). hsp16(Mtb) occurs in the early stage of SA, whereas hsp70(Mtb) occurs in stage II of SA. hsp65(Mtb) is highly expressed in the capillary vessels in lymph node tissues in patients with SA.

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