PrP Amyloid Plaques in Creutzfeldt-Jakob Disease of Short Duration: Immunohistochemical Studies of 5 Cases from Poland
Overview
Overview
Authors
Affiliations
Affiliations
Soon will be listed here.
Abstract
We report here PrP-immunohistochemistry performed on brains from CJD cases from Poland. Only one of five definitive CJD cases exhibited typical PrP-immunoreactive kuru-like plaques and this was case of a short duration. We thus confirm the low frequency of PrP plaques in CJD of Eastern and Central European origin.
Citing Articles
Liberski P Mol Neurobiol. 1994; 8(1):67-77.
PMID: 7522013 DOI: 10.1007/BF02778009.
References
1.
Adams H, Beck E, Shenkin A
. Creutzfeldt-Jakob disease: further similarities with kuru. J Neurol Neurosurg Psychiatry. 1974; 37(2):195-200.
PMC: 494608.
DOI: 10.1136/jnnp.37.2.195.
View
2.
Prusiner S, McKinley M, Bowman K, Bolton D, Bendheim P, Groth D
. Scrapie prions aggregate to form amyloid-like birefringent rods. Cell. 1983; 35(2 Pt 1):349-58.
DOI: 10.1016/0092-8674(83)90168-x.
View
3.
Goldgaber D, Goldfarb L, Brown P, Asher D, Brown W, Lin S
. Mutations in familial Creutzfeldt-Jakob disease and Gerstmann-Sträussler-Scheinker's syndrome. Exp Neurol. 1989; 106(2):204-6.
DOI: 10.1016/0014-4886(89)90095-2.
View
4.
Boellaard J, Schlote W
. [Subacute spongiform encephalopathy with multiform plaque formation. "Peculiar familial-hereditary disease of CNS [spinocerebellar atrophy with dementia, plaques, and plaque-like deposits in cerebellum and cerebrum" (Gerstmann, Sträussler,...]. Acta Neuropathol. 1980; 49(3):205-12.
DOI: 10.1007/BF00707108.
View
5.
Merz P, Somerville R, Wisniewski H, Manuelidis L, MANUELIDIS E
. Scrapie-associated fibrils in Creutzfeldt-Jakob disease. Nature. 1983; 306(5942):474-6.
DOI: 10.1038/306474a0.
View