Current Advances in Local Protein Synthesis and Synaptic Plasticity

Overview

Journal J Neurosci

Specialty Neurology

Date 2006 Jul 11

PMID 16822970

Citations 65

Authors

Brad E Pfeiffer

Kimberly M Huber

Affiliations

Soon will be listed here.

Abstract

Local or dendritic protein synthesis is required for long-term functional synaptic change, such as long-term potentiation (LTP) and long-term depression (LTD). LTP and LTD both rely on similar signal transduction cascades, which regulate translation initiation. Current research indicates that the specificity by which new proteins participate in either LTP or LTD may be determined in part by specific RNA-binding proteins as well as activity-dependent capture.

Citing Articles

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