Brad E Pfeiffer
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Explore the profile of Brad E Pfeiffer including associated specialties, affiliations and a list of published articles.
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23
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1968
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Recent Articles
1.
Berndt M, Trusel M, Roberts T, Pfeiffer B, Volk L
Neuron
. 2023 Sep;
111(19):2984-2994.e4.
PMID: 37689058
Neuronal activity during experience is thought to induce plastic changes within the hippocampal network that underlie memory formation, although the extent and details of such changes in vivo remain unclear....
2.
Quigley L, Pendry R, Mendoza M, Pfeiffer B, Volk L
Cell Rep
. 2023 Jun;
42(6):112662.
PMID: 37347662
Synaptic plasticity is hypothesized to underlie "replay" of salient experience during hippocampal sharp-wave/ripple (SWR)-based ensemble activity and to facilitate systems-level memory consolidation coordinated by SWRs and cortical sleep spindles. It...
3.
Pendry R, Quigley L, Volk L, Pfeiffer B
J Vis Exp
. 2023 Jun;
(196).
PMID: 37335110
In vivo electrophysiology provides unparalleled insight into the sub-second-level circuit dynamics of the intact brain and represents a method of particular importance for studying mouse models of human neuropsychiatric disorders....
4.
Pendry R, Quigley L, Volk L, Pfeiffer B
bioRxiv
. 2023 Jan;
PMID: 36711560
Short Abstract: We describe a novel micro-drive design, surgical implantation procedure, and post-surgery recovery strategy that allows for chronic field and single-unit recordings from up to sixteen brain regions simultaneously...
5.
Umbach G, Tan R, Jacobs J, Pfeiffer B, Lega B
Nat Commun
. 2022 Oct;
13(1):6162.
PMID: 36257934
Episodic memories, or consciously accessible memories of unique events, represent a key aspect of human cognition. Evidence from rodent models suggests that the neural representation of these complex memories requires...
6.
Pfeiffer B
J Neurosci
. 2022 Apr;
42(19):3975-3988.
PMID: 35396328
The hippocampus is critical for rapid acquisition of many forms of memory, although the circuit-level mechanisms through which the hippocampus rapidly consolidates novel information are unknown. Here, the activity of...
7.
Berners-Lee A, Feng T, Silva D, Wu X, Ambrose E, Pfeiffer B, et al.
Neuron
. 2022 Apr;
110(11):1829-1842.e5.
PMID: 35381188
The hippocampus is implicated in memory formation, and neurons in the hippocampus take part in replay sequences that have been proposed to reflect memory of explored space. By recording from...
8.
Umbach G, Kantak P, Jacobs J, Kahana M, Pfeiffer B, Sperling M, et al.
Proc Natl Acad Sci U S A
. 2020 Oct;
117(45):28463-28474.
PMID: 33109718
The organization of temporal information is critical for the encoding and retrieval of episodic memories. In the rodent hippocampus and entorhinal cortex, evidence accumulated over the last decade suggests that...
9.
Wang M, Foster D, Pfeiffer B
Science
. 2020 Oct;
370(6513):247-250.
PMID: 33033222
Neural networks display the ability to transform forward-ordered activity patterns into reverse-ordered, retrospective sequences. The mechanisms underlying this transformation remain unknown. We discovered that, during active navigation, rat hippocampal CA1...
10.
Kelly E, Meng F, Fujita H, Morgado F, Kazemi Y, Rice L, et al.
Nat Neurosci
. 2020 Jul;
23(9):1102-1110.
PMID: 32661395
Cerebellar dysfunction has been demonstrated in autism spectrum disorders (ASDs); however, the circuits underlying cerebellar contributions to ASD-relevant behaviors remain unknown. In this study, we demonstrated functional connectivity between the...