Alpha 2.0
Login Register
» Articles » PMID: 1678809

Diagnosis of Cysticercosis in Endemic Regions. The Cysticercosis Working Group in Peru

Overview
Journal Lancet
Publisher Elsevier
Specialty General Medicine
Date 1991 Aug 31
PMID 1678809
Citations 23
Authors
H H Garcia
M Martinez
R Gilman
G Herrera
V C Tsang
J B Pilcher
F Diaz
M Verastegui
C Gallo
M Porras
Affiliations
Soon will be listed here.
Abstract

Taenia solium cysticercosis is a frequent cause of neurological disease in developing countries. Specific diagnosis of cysticercosis is difficult. We obtained serum and/or CSF samples from 204 consecutive patients admitted to a neurological ward in Lima, Peru, and looked for antibodies specific for T solium with the enzyme-linked immunoelectrotransfer blot (EITB) assay. 21 (12%) of 173 serum samples from these patients were EITB-positive. In contrast, only 2 (1.5%) of 135 patients attending a public endoscopy clinic and 1 (1%) of 88 patients attending a private endoscopy clinic were seropositive. 1 (1%) of 98 pregnant women living in a Lima shanty town was EITB-positive. 15 (58%) of 26 neurology patients diagnosed clinically as having cysticercosis were seronegative. Routine screening by EITB of all patients with neurological symptoms from areas of endemic cysticercosis would avoid misdiagnosis of this common and treatable disease.

Citing Articles

Intradural extramedullary cystic lesions: an interesting cauda equina cysticercosis case report and a literature review.

Sun Y, Gao S, Liu H, Meng C BMC Neurol. 2024; 24(1):431.

PMID: 39501199 PMC: 11536695. DOI: 10.1186/s12883-024-03941-4.

Development and evaluation of time-resolved rapid immunofluorescence test for detection of TSOL18 specific antibody in porcine cysticercosis infections.

Zhang D, Duan R, Liu J, Wang M, Yang Y, Zhao Y BMC Vet Res. 2024; 20(1):182.

PMID: 38720329 PMC: 11077887. DOI: 10.1186/s12917-024-04034-7.

Amplification of cestode DNA from the peri-anal region of naturally infected foxes by PCR and LAMP: proof of concept for a potential sampling strategy for diagnosing human taeniosis.

Muchaamba G, Alvarez Rojas C, Deplazes P Parasitol Res. 2021; 120(10):3451-3459.

PMID: 34462804 PMC: 8405393. DOI: 10.1007/s00436-021-07271-z.

Pharmacokinetics, Safety, and Tolerability of Oxfendazole in Healthy Volunteers: a Randomized, Placebo-Controlled First-in-Human Single-Dose Escalation Study.

An G, Murry D, Gajurel K, Bach T, Deye G, Stebounova L Antimicrob Agents Chemother. 2019; 63(4).

PMID: 30745383 PMC: 6437481. DOI: 10.1128/AAC.02255-18.

Mathematical model of the life cycle of taenia-cysticercosis: transmission dynamics and chemotherapy (Part 1).

Jose M, Bobadilla J, Sanchez-Torres N, Laclette J Theor Biol Med Model. 2018; 15(1):18.

PMID: 30449280 PMC: 6241031. DOI: 10.1186/s12976-018-0090-0.

References
1.
Nava Segura J . [Cysticercosis of the central nervous system]. Salud Publica Mex. 1983; 25(3):297-300. View
2.
Takayanagui O, Jardim E . [Clinical aspects of neurocysticercosis: analysis of 500 cases]. Arq Neuropsiquiatr. 1983; 41(1):50-63. DOI: 10.1590/s0004-282x1983000100004. View
3.
Nash T, NEVA F . Recent advances in the diagnosis and treatment of cerebral cysticercosis. N Engl J Med. 1984; 311(23):1492-6. DOI: 10.1056/NEJM198412063112307. View
4.
Loo L, BRAUDE A . Cerebral cysticercosis in San Diego. A report of 23 cases and a review of the literature. Medicine (Baltimore). 1982; 61(6):341-59. View
5.
McCORMICK G, Zee C, Heiden J . Cysticercosis cerebri. Review of 127 cases. Arch Neurol. 1982; 39(9):534-9. DOI: 10.1001/archneur.1982.00510210004002. View