Efficacy of Voriconazole in a Guinea Pig Model of Invasive Trichosporonosis

Overview

Journal Antimicrob Agents Chemother

Publisher American Society for Microbiology

Specialty Pharmacology

Date 2006 May 26

PMID 16723595

Citations 11

Authors

Carolina Serena

Felix Gilgado

Marcal Marine

F Javier Pastor

Josep Guarro

Affiliations

Soon will be listed here.

Abstract

We have evaluated the efficacy of voriconazole (VRC) in a systemic infection by Trichosporon asahii in immunosuppressed guinea pigs. VRC was more effective than amphotericin B in prolonging survival and reducing tissue burden. The best results were obtained with VRC at 10 mg/kg of body weight/day.

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