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Host Defence Peptides from Invertebrates--emerging Antimicrobial Strategies

Overview
Journal Immunobiology
Publisher Elsevier
Date 2006 May 16
PMID 16697922
Citations 87
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Abstract

Cationic antimicrobial (host defence) peptides are found as potent components of the innate immune system of all invertebrates in which they have been investigated. They vary substantially in their amino acid sequences, secondary structures, inducibility, potency and antimicrobial activity spectra. This enormous diversity is providing templates for the design and development of both antibiotic peptides and peptides that selectively modulate innate immunity to increase protection against infections and sepsis.

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