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Histone H4 Lysine 16 Acetylation Breaks the Genome's Silence

Overview
Journal Genome Biol
Specialties Biology
Genetics
Date 2006 May 13
PMID 16689998
Citations 26
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Abstract

Acetylation at histone H4 lysine 16 is involved in many cellular processes in organisms as diverse as yeast and humans. A recent biochemical study pinpoints this particular acetylation mark as a switch for changing chromatin from a repressive to a transcriptionally active state.

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References
1.
Shia W, Osada S, Florens L, Swanson S, Washburn M, Workman J . Characterization of the yeast trimeric-SAS acetyltransferase complex. J Biol Chem. 2005; 280(12):11987-94. DOI: 10.1074/jbc.M500276200. View

2.
Eberharter A, Becker P . Histone acetylation: a switch between repressive and permissive chromatin. Second in review series on chromatin dynamics. EMBO Rep. 2002; 3(3):224-9. PMC: 1084017. DOI: 10.1093/embo-reports/kvf053. View

3.
Straub T, Dahlsveen I, Becker P . Dosage compensation in flies: mechanism, models, mystery. FEBS Lett. 2005; 579(15):3258-63. DOI: 10.1016/j.febslet.2005.03.050. View

4.
Allfrey V, Faulkner R, Mirsky A . ACETYLATION AND METHYLATION OF HISTONES AND THEIR POSSIBLE ROLE IN THE REGULATION OF RNA SYNTHESIS. Proc Natl Acad Sci U S A. 1964; 51:786-94. PMC: 300163. DOI: 10.1073/pnas.51.5.786. View

5.
Akhtar A, Becker P . Activation of transcription through histone H4 acetylation by MOF, an acetyltransferase essential for dosage compensation in Drosophila. Mol Cell. 2000; 5(2):367-75. DOI: 10.1016/s1097-2765(00)80431-1. View