First Report of Knockdown Mutations in the Malaria Vector Anopheles Gambiae from Cameroon

Overview

Journal Am J Trop Med Hyg

Specialty Tropical Medicine

Date 2006 May 12

PMID 16687682

Citations 71

Authors

Josiane Etang

Etienne Fondjo

Fabrice Chandre

Isabelle Morlais

Cecile Brengues

Philippe Nwane

Mouhamadou Chouaibou

Hamadou Ndjemai

Frederic Simard

Affiliations

Soon will be listed here.

Abstract

We report the first finding of the knockdown Leu-Phe and Leu-Ser mutations associated with resistance to pyrethroids and DDT insecticides in the malaria mosquito Anopheles gambiae from Cameroon. The Leu-Phe mutation was found in both the M and S molecular forms of An. gambiae. Importantly, two specimens of the S molecular form were found to carry both mutations in a heterozygous state.

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