The Long Journey from Stem Cells to Medical Product

Overview

Journal Cell

Publisher Cell Press

Specialty Cell Biology

Date 2006 Apr 18

PMID 16615881

Citations 13

Authors

Ann Parson

Affiliations

Soon will be listed here.

Abstract

There is much interest in developing stem cells and the cells derived from them as therapies for treating human disease and injury, but many biological, technological and regulatory hurdles have to be overcome before these cell therapies can be brought to commercial fruition.

Citing Articles

Impact of poloxamer 188 (Pluronic F-68) additive on cell mechanical properties, quantification by real-time deformability cytometry.

Guzniczak E, Jimenez M, Irwin M, Otto O, Willoughby N, Bridle H Biomicrofluidics. 2019; 12(4):044118.

PMID: 30867863 PMC: 6404947. DOI: 10.1063/1.5040316.

High-throughput assessment of mechanical properties of stem cell derived red blood cells, toward cellular downstream processing.

Guzniczak E, Mohammad Zadeh M, Dempsey F, Jimenez M, Bock H, Whyte G Sci Rep. 2017; 7(1):14457.

PMID: 29089557 PMC: 5663858. DOI: 10.1038/s41598-017-14958-w.

The potential impact of bone tissue engineering in the clinic.

Mishra R, Bishop T, Valerio I, Fisher J, Dean D Regen Med. 2016; 11(6):571-87.

PMID: 27549369 PMC: 5007661. DOI: 10.2217/rme-2016-0042.

AAOS Research Symposium Updates and Consensus: Biologic Treatment of Orthopaedic Injuries.

LaPrade R, Dragoo J, Koh J, Murray I, Geeslin A, Chu C J Am Acad Orthop Surg. 2016; 24(7):e62-78.

PMID: 27227987 PMC: 6548434. DOI: 10.5435/JAAOS-D-16-00086.

Challenges in the translation and commercialization of cell therapies.

Dodson B, Levine A BMC Biotechnol. 2015; 15:70.

PMID: 26250902 PMC: 4528687. DOI: 10.1186/s12896-015-0190-4.