Seroprevalence of Helicobacter Pylori in Dyspeptic Patients and Its Relationship with HIV Infection, ABO Blood Groups and Life Style in a University Hospital, Northwest Ethiopia
Overview
Authors
Affiliations
Aim: To determine the prevalence of Helicobacter pylori (H pylori) among dyspeptic patients and to assess the relationship between H pylori infection, blood group, HIV infection and life style of the patients.
Methods: In a hospital-based cross-sectional study, patients attending Outpatient Department of University of Gondar Hospital were enrolled. Socio-demographic information was collected using questionnaires. Serum was analyzed for anti-H pylori IgG antibodies using a commercial kit. HIV serostatus was determined by enzyme-linked immunosorbent assay (ELISA). Blood grouping was performed by slide agglutination tests.
Results: A total of 215 dyspeptic patients were included in the study. One hundred and sixteen patients (54%) were females and 99 (46%) were males. Anti-H pylori IgG antibodies were detected in sera of 184 (85.6%) patients. The prevalence was significantly higher in patients aged 50 years and above. Twenty point five percent of the patients were found to be seropositive for HIV. No significant association was found between sex, ABO blood groups, consumption of spicy diets, socio-economic status and seropositivity for H pylori. However, alcohol consumption was significantly associated with H pylori serology.
Conclusion: The prevalence of H pylori infection is associated with a history of alcohol intake and older age. The effect of different diet, alcohol and socioeconomic status as risk factors for H pylori infection needs further study.
Alaridah N, Joudeh R, Jarrar R, AlRefaei A, Shewaikani N, Nassr H Cureus. 2024; 16(2):e55018.
PMID: 38550406 PMC: 10973923. DOI: 10.7759/cureus.55018.
Abadi T, Teklu T, Wondmagegn T, Alem M, Desalegn G Eur J Med Res. 2024; 29(1):178.
PMID: 38494500 PMC: 10946129. DOI: 10.1186/s40001-024-01750-6.
Mnichil Z, Nibret E, Hailegebriel T, Demelash M, Mekonnen D Braz J Microbiol. 2023; 55(1):51-64.
PMID: 38040991 PMC: 10920553. DOI: 10.1007/s42770-023-01190-0.
Blood Type and Outcomes in Pregnant Women with Placenta Previa.
Fan D, Rao J, Zhang H, Lin D, Guo X, Liu Z Oxid Med Cell Longev. 2023; 2023:4725064.
PMID: 36743690 PMC: 9891818. DOI: 10.1155/2023/4725064.
Mesfun M, Gliga S, Fuchs A, Orth H, Schonfeld A, Luedde T IJID Reg. 2022; 2:169-174.
PMID: 35757079 PMC: 9216691. DOI: 10.1016/j.ijregi.2022.01.007.