Living Dangerously: How Helicobacter Pylori Survives in the Human Stomach

Overview

Journal Nat Rev Mol Cell Biol

Specialties Cell Biology
Molecular Biology

Date 2001 Jun 5

PMID 11389469

Citations 159

Authors

C Montecucco

R Rappuoli

Affiliations

Soon will be listed here.

Abstract

Helicobacter pylori was already present in the stomach of primitive humans as they left Africa and spread through the world. Today, it still chronically infects more than 50% of the human population, causing, in some cases, severe diseases such as peptic ulcers and stomach cancer. To succeed in these long-term associations, H. pylori has developed a unique set of virulence factors, which allow survival in a unique and hostile ecological niche--the human stomach.

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