The Effect of Acute Poisoning with Potassium Nitrate and Sodium Nitrite on the Processes of Intestinal Absorption of D-xylose in Rats

Overview

Journal Arch Environ Contam Toxicol

Specialty Environmental Health

Date 1991 Sep 1

PMID 1659333

Citations 1

Authors

I Grudzinski

A Szymanski

Affiliations

Soon will be listed here.

Abstract

The intestinal transport of D-xylose was studied during the acute poisoning of male Wistar rats with orally administered potassium nitrate and sodium nitrite. At the peak of xylose absorption, the metabolic parameters of Na+/K(+)-ATPase, alkaline phosphatase, oxygen uptake, and lactic acid level were determined in the small intestine mucosa. Nitrite in a dose of 80 mg NaNO2/kg b.w. increased the permeability of gastric mucosa for D-xylose and raised the uptake of oxygen by the small intestine mucosa. No changes were observed in the activity of Na+/K(+)-ATPase and alkaline phosphatase. A dose of 10 mg NaNO2/kg b.w. was not followed by increased absorption of this sugar. It was also demonstrated that potassium nitrate had no effect on the process of intestinal absorption of D-xylose and failed to change the determined metabolic parameters of the small intestine mucosa.

Citing Articles

Effect of nitrite on ureagenesis and carbohydrate metabolism in isolated rat hepatocytes.

Wiechetek M, Garwacki S, Karlik W, LEWICKI J, Souffrant W Arch Environ Contam Toxicol. 1993; 24(3):375-80.

PMID: 8470937 DOI: 10.1007/BF01128737.

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