Entire Potato Consumption Improves Lipid Metabolism and Antioxidant Status in Cholesterol-fed Rat

Overview

Journal Eur J Nutr

Specialty Nutritional Sciences

Date 2006 Apr 6

PMID 16586150

Citations 8

Authors

Laetitia Robert

Agnes Narcy

Edmond Rock

Christian Demigne

Andrzej Mazur

Christian Remesy

Affiliations

Soon will be listed here.

Abstract

Background: Vegetables and fruits are rich sources of a variety of nutrients, including vitamins (E and C), trace minerals, and dietary fibers, and many other classes of biologically active compounds such as carotenoids and polyphenols, which are often assumed to protect against degenerative pathologies such as cardiovascular diseases. Although potato is considered as a starchy food, it is also included in the category of vegetables by its micronutrient content.

Aim Of The Study: In the present study, we investigated in the rat the effect of a potato-enriched diet on lipid metabolism and antioxidant protection.

Results: Feeding rats a potato-enriched diet for 3 weeks led to a significant decrease in cholesterol and triglyceride levels in plasma (respectively, -30%, P<0.0001 and -36%, P<0.05) and cholesterol level in liver (-42%, P<0.0001). Antioxidant status was also improved by potato consumption. TBARS levels in heart were decreased and vitamin E/triglycerides ratio in plasma was improved.

Conclusions: Our present results suggest that consumption of cooked potatoes (consumed with skin) may enhance antioxidant defense and improve the lipid metabolism. These effects could be interesting for prevention of cardiovascular disease.

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References

Aprikian O, Duclos V, Guyot S, Besson C, Manach C, Bernalier A . Apple pectin and a polyphenol-rich apple concentrate are more effective together than separately on cecal fermentations and plasma lipids in rats. J Nutr. 2003; 133(6):1860-5. DOI: 10.1093/jn/133.6.1860. View

Englyst H, Cummings J . Digestion of polysaccharides of potato in the small intestine of man. Am J Clin Nutr. 1987; 45(2):423-31. DOI: 10.1093/ajcn/45.2.423. View

Moundras C, Behr S, Remesy C, Demigne C . Fecal losses of sterols and bile acids induced by feeding rats guar gum are due to greater pool size and liver bile acid secretion. J Nutr. 1997; 127(6):1068-76. DOI: 10.1093/jn/127.6.1068. View

Mathers J, Dawson L . Large bowel fermentation in rats eating processed potatoes. Br J Nutr. 1991; 66(2):313-29. DOI: 10.1079/bjn19910034. View

Lyan B, Azais-Braesco V, Cardinault N, Tyssandier V, Borel P, Grolier P . Simple method for clinical determination of 13 carotenoids in human plasma using an isocratic high-performance liquid chromatographic method. J Chromatogr B Biomed Sci Appl. 2001; 751(2):297-303. DOI: 10.1016/s0378-4347(00)00488-6. View

Fernandez M . Distinct mechanisms of plasma LDL lowering by dietary fiber in the guinea pig: specific effects of pectin, guar gum, and psyllium. J Lipid Res. 1995; 36(11):2394-404. View

Chu Y, Sun J, Wu X, Liu R . Antioxidant and antiproliferative activities of common vegetables. J Agric Food Chem. 2002; 50(23):6910-6. DOI: 10.1021/jf020665f. View

Baig M, Cerda J . Pectin: its interaction with serum lipoproteins. Am J Clin Nutr. 1981; 34(1):50-3. DOI: 10.1093/ajcn/34.1.50. View

Andlauer W, Stumpf C, Hubert M, Rings A, Furst P . Influence of cooking process on phenolic marker compounds of vegetables. Int J Vitam Nutr Res. 2003; 73(2):152-9. DOI: 10.1024/0300-9831.73.2.152. View

10.

Agudo A, Slimani N, Ocke M, Naska A, Miller A, Kroke A . Consumption of vegetables, fruit and other plant foods in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohorts from 10 European countries. Public Health Nutr. 2003; 5(6B):1179-96. DOI: 10.1079/PHN2002398. View

11.

Gallant D, Bouchet B, Buleon A, Perez S . Physical characteristics of starch granules and susceptibility to enzymatic degradation. Eur J Clin Nutr. 1992; 46 Suppl 2:S3-16. View

12.

Djousse L, Arnett D, Coon H, Province M, Moore L, Ellison R . Fruit and vegetable consumption and LDL cholesterol: the National Heart, Lung, and Blood Institute Family Heart Study. Am J Clin Nutr. 2004; 79(2):213-7. DOI: 10.1093/ajcn/79.2.213. View

13.

Mazur A, Remesy C, Gueux E, Levrat M, Demigne C . Effects of diets rich in fermentable carbohydrates on plasma lipoprotein levels and on lipoprotein catabolism in rats. J Nutr. 1990; 120(9):1037-45. DOI: 10.1093/jn/120.9.1037. View

14.

Anderson J, Bridges S . Dietary fiber content of selected foods. Am J Clin Nutr. 1988; 47(3):440-7. DOI: 10.1093/ajcn/47.3.440. View

15.

Behr S, Mustad V, Remesy C, Demigne C . Low levels of viscous hydrocolloids lower plasma cholesterol in rats primarily by impairing cholesterol absorption. J Nutr. 2000; 130(2):243-8. DOI: 10.1093/jn/130.2.243. View

16.

Van Hoydonck P, Schouten E, Manuel-Y-Keenoy B, Van Campenhout A, Hoppenbrouwers K, Temme E . Does vitamin C supplementation influence the levels of circulating oxidized LDL, sICAM-1, sVCAM-1 and vWF-antigen in healthy male smokers?. Eur J Clin Nutr. 2004; 58(12):1587-93. DOI: 10.1038/sj.ejcn.1601990. View

17.

Lasheras C, Gonzalez S, Huerta J, Lombardia C, Ibanez R, Patterson A . Food habits are associated with lipid peroxidation in an elderly population. J Am Diet Assoc. 2003; 103(11):1480-7. DOI: 10.1016/j.jada.2003.08.023. View

18.

Ness A, Powles J . Fruit and vegetables, and cardiovascular disease: a review. Int J Epidemiol. 1997; 26(1):1-13. DOI: 10.1093/ije/26.1.1. View

19.

Lee H, Shoeman D, Csallany A . Urinary response to in vivo lipid peroxidation induced by vitamin E deficiency. Lipids. 1992; 27(2):124-8. DOI: 10.1007/BF02535811. View

20.

Block G, Patterson B, Subar A . Fruit, vegetables, and cancer prevention: a review of the epidemiological evidence. Nutr Cancer. 1992; 18(1):1-29. DOI: 10.1080/01635589209514201. View