Expression of Na,K-ATPase Isoforms in Human Heart

Overview

Journal Biochem Biophys Res Commun

Publisher Elsevier

Specialty Biochemistry

Date 1991 Sep 30

PMID 1656951

Citations 16

Authors

O I Shamraj

D Melvin

J B Lingrel

Affiliations

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Abstract

The expression pattern of the multiple isoforms of Na,K-ATPase was examined in the human heart. Isoform specific oligonucleotide probes for the alpha 1, alpha 2, alpha 3 and beta 1 subunits were used to probe Northern blots. The adult human ventricle expresses mRNAs for all three alpha subunit isoforms in addition to beta 1 subunit mRNA.

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