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Effect of Clavulanic Acid on Anaerobic Bacteria Resistant to Beta-lactam Antibiotics

Overview
Journal Antimicrob Agents Chemother
Publisher American Society for Microbiology
Specialty Pharmacology
Date 1978 Jan 1
PMID 16557674
Citations 20
Authors
J Wust
T D Wilkins
Affiliations
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Abstract

The minimum inhibitory concentrations of penicillin and cephalothin necessary to inhibit growth of most anaerobic bacteria were reduced to a susceptible level by 1 to 5 mug of clavulanic acid per ml. In most cases, minimum inhibitory concentrations of cefoxitin were not affected.

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References
1.
Murray P, Rosenblatt J . Penicillin resistance and penicillinase production in clinical isolates of Bacteroides melaninogenicus. Antimicrob Agents Chemother. 1977; 11(4):605-8. PMC: 352036. DOI: 10.1128/AAC.11.4.605. View
2.
Salyers A, Wong J, Wilkins T . Beta-Lactamase activity in strains of Bacteroides melaninogenicus and Bacteroides oralis. Antimicrob Agents Chemother. 1977; 11(1):142-6. PMC: 351933. DOI: 10.1128/AAC.11.1.142. View
3.
Reading C, Cole M . Clavulanic acid: a beta-lactamase-inhiting beta-lactam from Streptomyces clavuligerus. Antimicrob Agents Chemother. 1977; 11(5):852-7. PMC: 352086. DOI: 10.1128/AAC.11.5.852. View
4.
Darland G, Birnbaum J . Cefoxitin resistance to beta-lactamase: a major factor for susceptibility of bacteroides fragilis to the antibiotic. Antimicrob Agents Chemother. 1977; 11(4):725-34. PMC: 352058. DOI: 10.1128/AAC.11.4.725. View
5.
Weinrich A, Del Bene V . Beta-lactamase activity in anaerobic bacteria. Antimicrob Agents Chemother. 1976; 10(1):106-11. PMC: 429697. DOI: 10.1128/AAC.10.1.106. View