» Articles » PMID: 16515719

On the Evolution of the Standard Amino-acid Alphabet

Overview
Journal Genome Biol
Specialties Biology
Genetics
Date 2006 Mar 7
PMID 16515719
Citations 16
Authors
Affiliations
Soon will be listed here.
Abstract

Although one standard amino-acid 'alphabet' is used by most organisms on Earth, the evolutionary cause(s) and significance of this alphabet remain elusive. Fresh insights into the origin of the alphabet are now emerging from disciplines as diverse as astrobiology, biochemical engineering and bioinformatics.

Citing Articles

Analysis of the efficacy, safety, and cost of alternative forms of creatine available for purchase on Amazon.com: are label claims supported by science?.

Escalante G, Gonzalez A, St Mart D, Torres M, Echols J, Islas M Heliyon. 2022; 8(12):e12113.

PMID: 36544833 PMC: 9761713. DOI: 10.1016/j.heliyon.2022.e12113.


Protein-protein interaction prediction with deep learning: A comprehensive review.

Soleymani F, Paquet E, Viktor H, Michalowski W, Spinello D Comput Struct Biotechnol J. 2022; 20:5316-5341.

PMID: 36212542 PMC: 9520216. DOI: 10.1016/j.csbj.2022.08.070.


Deciphering the conformational landscape of few selected aromatic noncoded amino acids (NCAAs) for applications in rational design of peptide therapeutics.

Behera L, Ghosh M, Rana S Amino Acids. 2022; 54(8):1183-1202.

PMID: 35723743 PMC: 9207436. DOI: 10.1007/s00726-022-03175-z.


Improved l-phenylglycine synthesis by introducing an engineered cofactor self-sufficient system.

Wang P, Zhang X, Tao Y, Lv X, Cheng S, Liu C Synth Syst Biotechnol. 2022; 7(1):513-521.

PMID: 35024478 PMC: 8715069. DOI: 10.1016/j.synbio.2021.12.008.


Commentary on Urinary l-erythro-β-hydroxyasparagine: a novel serine racemase inhibitor and substrate of the Zn2+-dependent d-serine dehydratase.

Tamaki F Biosci Rep. 2021; 41(12).

PMID: 34874398 PMC: 8662797. DOI: 10.1042/BSR20211524C.


References
1.
Henikoff S, Henikoff J . Amino acid substitution matrices from protein blocks. Proc Natl Acad Sci U S A. 1992; 89(22):10915-9. PMC: 50453. DOI: 10.1073/pnas.89.22.10915. View

2.
Shakhnovich B, Deeds E, DeLisi C, Shakhnovich E . Protein structure and evolutionary history determine sequence space topology. Genome Res. 2005; 15(3):385-92. PMC: 551565. DOI: 10.1101/gr.3133605. View

3.
Taverna D, Goldstein R . Why are proteins so robust to site mutations?. J Mol Biol. 2002; 315(3):479-84. DOI: 10.1006/jmbi.2001.5226. View

4.
Walter K, Vamvaca K, Hilvert D . An active enzyme constructed from a 9-amino acid alphabet. J Biol Chem. 2005; 280(45):37742-6. DOI: 10.1074/jbc.M507210200. View

5.
Uy R, Wold F . Posttranslational covalent modification of proteins. Science. 1977; 198(4320):890-6. DOI: 10.1126/science.337487. View