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Multilocus Genotyping of Cryptosporidium Sp. Isolates from Human Immunodeficiency Virus-infected Individuals in South India

Abstract

This study characterized cryptosporidial infections in 48 human immunodeficiency virus-infected individuals in India by multilocus genotyping. Cryptosporidium hominis, C. parvum, C. felis, C. muris, and C. meleagridis were identified. Cpgp40/15 PCR-restriction fragment length polymorphism identified six subgenotypes. Cryptosporidial diarrhea was associated with decreased CD4 counts, below 200 (P = 0.009), but not high viral loads.

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References
1.
Cevallos A, Zhang X, Waldor M, Jaison S, Zhou X, Tzipori S . Molecular cloning and expression of a gene encoding Cryptosporidium parvum glycoproteins gp40 and gp15. Infect Immun. 2000; 68(7):4108-16. PMC: 101706. DOI: 10.1128/IAI.68.7.4108-4116.2000. View

2.
McLAUCHLIN J, Pedraza-Diaz S, Nichols G . Genetic characterization of Cryptosporidium strains from 218 patients with diarrhea diagnosed as having sporadic cryptosporidiosis. J Clin Microbiol. 1999; 37(10):3153-8. PMC: 85515. DOI: 10.1128/JCM.37.10.3153-3158.1999. View

3.
McLAUCHLIN J, Amar C, Pedraza-Diaz S, Nichols G . Molecular epidemiological analysis of Cryptosporidium spp. in the United Kingdom: results of genotyping Cryptosporidium spp. in 1,705 fecal samples from humans and 105 fecal samples from livestock animals. J Clin Microbiol. 2000; 38(11):3984-90. PMC: 87529. DOI: 10.1128/JCM.38.11.3984-3990.2000. View

4.
KOSEK M, Alcantara C, Lima A, Guerrant R . Cryptosporidiosis: an update. Lancet Infect Dis. 2002; 1(4):262-9. DOI: 10.1016/S1473-3099(01)00121-9. View

5.
Gatei W, Ashford R, Beeching N, Kamwati S, Greensill J, Hart C . Cryptosporidium muris infection in an HIV-infected adult, Kenya. Emerg Infect Dis. 2002; 8(2):204-6. PMC: 2732451. DOI: 10.3201/eid0802.010256. View