Occurrence of OXA-58-like Carbapenemases in Acinetobacter Spp. Collected over 10 Years in Three Continents

Overview

Journal Antimicrob Agents Chemother

Publisher American Society for Microbiology

Specialty Pharmacology

Date 2006 Jan 27

PMID 16436738

Citations 39

Authors

Juliana Coelho

Neil Woodford

Mariya Afzal-Shah

David Livermore

Affiliations

Soon will be listed here.

Abstract

OXA-58 is a recently described carbapenemase from Acinetobacter spp. in Europe. We examined earlier worldwide Acinetobacter collections and found bla(OXA-58) in 30 carbapenem-nonsusceptible isolates, including several isolates collected in Argentina and Kuwait in 1995 and 1996 and in a British outbreak strain from 2000. Most isolates (28 of 30) also had bla(OXA-51). We conclude that bla(OXA-58) is geographically widespread and has occurred in Acinetobacter spp. for over 10 years.

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References

Donald H, Scaife W, Amyes S, Young H . Sequence analysis of ARI-1, a novel OXA beta-lactamase, responsible for imipenem resistance in Acinetobacter baumannii 6B92. Antimicrob Agents Chemother. 1999; 44(1):196-9. PMC: 89654. DOI: 10.1128/AAC.44.1.196-199.2000. View

Heritier C, Poirel L, Fournier P, Claverie J, Raoult D, Nordmann P . Characterization of the naturally occurring oxacillinase of Acinetobacter baumannii. Antimicrob Agents Chemother. 2005; 49(10):4174-9. PMC: 1251506. DOI: 10.1128/AAC.49.10.4174-4179.2005. View

Henwood C, Gatward T, Warner M, James D, Stockdale M, Spence R . Antibiotic resistance among clinical isolates of Acinetobacter in the UK, and in vitro evaluation of tigecycline (GAR-936). J Antimicrob Chemother. 2002; 49(3):479-87. DOI: 10.1093/jac/49.3.479. View

Woodford N, Ellington M, Coelho J, Turton J, Ward M, Brown S . Multiplex PCR for genes encoding prevalent OXA carbapenemases in Acinetobacter spp. Int J Antimicrob Agents. 2006; 27(4):351-3. DOI: 10.1016/j.ijantimicag.2006.01.004. View

Nordmann P, Poirel L . Emerging carbapenemases in Gram-negative aerobes. Clin Microbiol Infect. 2002; 8(6):321-31. DOI: 10.1046/j.1469-0691.2002.00401.x. View

Landman D, Quale J, Mayorga D, Adedeji A, Vangala K, Ravishankar J . Citywide clonal outbreak of multiresistant Acinetobacter baumannii and Pseudomonas aeruginosa in Brooklyn, NY: the preantibiotic era has returned. Arch Intern Med. 2002; 162(13):1515-20. DOI: 10.1001/archinte.162.13.1515. View

Lopez-Otsoa F, Gallego L, Towner K, Tysall L, Woodford N, Livermore D . Endemic carbapenem resistance associated with OXA-40 carbapenemase among Acinetobacter baumannii isolates from a hospital in northern Spain. J Clin Microbiol. 2002; 40(12):4741-3. PMC: 154648. DOI: 10.1128/JCM.40.12.4741-4743.2002. View

Ayan M, Durmaz R, Aktas E, Durmaz B . Bacteriological, clinical and epidemiological characteristics of hospital-acquired Acinetobacter baumannii infection in a teaching hospital. J Hosp Infect. 2003; 54(1):39-45. DOI: 10.1016/s0195-6701(03)00076-8. View

Dalla-Costa L, Coelho J, Souza H, Castro M, Stier C, Bragagnolo K . Outbreak of carbapenem-resistant Acinetobacter baumannii producing the OXA-23 enzyme in Curitiba, Brazil. J Clin Microbiol. 2003; 41(7):3403-6. PMC: 165295. DOI: 10.1128/JCM.41.7.3403-3406.2003. View

10.

Lee K, Lee W, Uh Y, Ha G, Cho J, Chong Y . VIM- and IMP-type metallo-beta-lactamase-producing Pseudomonas spp. and Acinetobacter spp. in Korean hospitals. Emerg Infect Dis. 2003; 9(7):868-71. PMC: 3023439. DOI: 10.3201/eid0907.020753. View

11.

Yu Y, Yang Q, Xu X, Kong H, Xu G, Zhong B . Typing and characterization of carbapenem-resistant Acinetobacter calcoaceticus-baumannii complex in a Chinese hospital. J Med Microbiol. 2004; 53(Pt 7):653-656. DOI: 10.1099/jmm.0.05513-0. View

12.

Silva G, Quinteira S, Bertolo E, Sousa J, Gallego L, Duarte A . Long-term dissemination of an OXA-40 carbapenemase-producing Acinetobacter baumannii clone in the Iberian Peninsula. J Antimicrob Chemother. 2004; 54(1):255-8. DOI: 10.1093/jac/dkh269. View

13.

Turton J, Kaufmann M, Warner M, Coelho J, Dijkshoorn L, Van Der Reijden T . A prevalent, multiresistant clone of Acinetobacter baumannii in Southeast England. J Hosp Infect. 2004; 58(3):170-9. DOI: 10.1016/j.jhin.2004.05.011. View

14.

Vaneechoutte M, Dijkshoorn L, Tjernberg I, Elaichouni A, de Vos P, Claeys G . Identification of Acinetobacter genomic species by amplified ribosomal DNA restriction analysis. J Clin Microbiol. 1995; 33(1):11-5. PMC: 227870. DOI: 10.1128/jcm.33.1.11-15.1995. View

15.

Scaife W, Young H, Paton R, Amyes S . Transferable imipenem-resistance in Acinetobacter species from a clinical source. J Antimicrob Chemother. 1995; 36(3):585-6. DOI: 10.1093/jac/36.3.585. View

16.

Ehrenstein B, Bernards A, Dijkshoorn L, Gerner-Smidt P, Towner K, Bouvet P . Acinetobacter species identification by using tRNA spacer fingerprinting. J Clin Microbiol. 1996; 34(10):2414-20. PMC: 229283. DOI: 10.1128/jcm.34.10.2414-2420.1996. View

17.

Afzal-Shah M, Villar H, Livermore D . Biochemical characteristics of a carbapenemase from an Acinetobacter baumannii isolate collected in Buenos Aires, Argentina. J Antimicrob Chemother. 1999; 43(1):127-31. DOI: 10.1093/jac/43.1.127. View

18.

Poirel L, Marque S, Heritier C, Segonds C, Chabanon G, Nordmann P . OXA-58, a novel class D {beta}-lactamase involved in resistance to carbapenems in Acinetobacter baumannii. Antimicrob Agents Chemother. 2004; 49(1):202-8. PMC: 538857. DOI: 10.1128/AAC.49.1.202-208.2005. View

19.

Heritier C, Dubouix A, Poirel L, Marty N, Nordmann P . A nosocomial outbreak of Acinetobacter baumannii isolates expressing the carbapenem-hydrolysing oxacillinase OXA-58. J Antimicrob Chemother. 2004; 55(1):115-8. DOI: 10.1093/jac/dkh500. View

20.

Brown S, Young H, Amyes S . Characterisation of OXA-51, a novel class D carbapenemase found in genetically unrelated clinical strains of Acinetobacter baumannii from Argentina. Clin Microbiol Infect. 2005; 11(1):15-23. DOI: 10.1111/j.1469-0691.2004.01016.x. View