Bacterial Nitration of 4-chlorobiphenyl

Overview

Journal Appl Environ Microbiol

Specialties Environmental Health
Microbiology

Date 1982 Oct 1

PMID 16346111

Citations 4

Authors

M Sylvestre

R Masse

F Messier

J Fauteux

J G Bisaillon

R Beaudet

Affiliations

Soon will be listed here.

Abstract

In the course of a study dealing with the biodegradation of 4-chlorobiphenyl by strain B-206, we noticed that the gram-negative bacterium accumulated different metabolic intermediates depending on the nitrogen source of the medium. Hence, in the presence of nitrate, strain B-206 produced four compounds which were identified as 2- and 4-hydroxy-4'-chlorobiphenyl and 2- and 4-hydroxy-mononitro-4'-chlorobiphenyl. The accumulation of these compounds in the culture medium indicated the presence of a monooxygenase in strain B-206 leading to the production of arene oxide intermediates. The possible transformation of 4-chlorobiphenyl to an arene oxide by this bacterial strain is a matter of concern because of the high reactivity of these arene oxides with biological material.

Citing Articles

Microbial biodegradation of 4-chlorobiphenyl, a model compound of chlorinated biphenyls.

Masse R, Messier F, Peloquin L, Ayotte C, Sylvestre M Appl Environ Microbiol. 1984; 47(5):947-51.

PMID: 6742836 PMC: 240022. DOI: 10.1128/aem.47.5.947-951.1984.

Influence of para-substituents on the oxidative metabolism of o-nitrophenols by Pseudomonas putida B2.

Zeyer J, Kocher H, Timmis K Appl Environ Microbiol. 1986; 52(2):334-9.

PMID: 3752997 PMC: 203526. DOI: 10.1128/aem.52.2.334-339.1986.

Novel biotransformations of 4-chlorobiphenyl by a Pseudomonas sp.

BARTON M, Crawford R Appl Environ Microbiol. 1988; 54(2):594-5.

PMID: 3355144 PMC: 202501. DOI: 10.1128/aem.54.2.594-595.1988.

Degradation of halogenated aromatic compounds.

Commandeur L, Parsons J Biodegradation. 1990; 1(2-3):207-20.

PMID: 1368148 DOI: 10.1007/BF00058837.

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