Recombination Between the DfrA12-orfF-aadA2 Cassette Array and an AadA1 Gene Cassette Creates a Hybrid Cassette, AadA8b

Overview

Journal Antimicrob Agents Chemother

Publisher American Society for Microbiology

Specialty Pharmacology

Date 2005 Oct 28

PMID 16251327

Citations 12

Authors

Alicia M Gestal

H W Stokes

Sally R Partridge

Ruth M Hall

Affiliations

Soon will be listed here.

Abstract

Homologous recombination between closely related gene cassettes, such as aadA1 and aadA2, which are 89% identical, can create hybrid cassettes and hybrids of existing cassette arrays. A new cassette array, dfrA12-orfF-aadA8b, which was created by such a recombination event occurring within the aadA2 cassette in the dfrA12-orfF-aadA2 array, has been identified.

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