Obesity As a Risk Factor in Venous Thromboembolism

Overview

Journal Am J Med

Specialty General Medicine

Date 2005 Sep 17

PMID 16164883

Citations 164

Authors

Paul D Stein

Afzal Beemath

Ronald E Olson

Affiliations

Soon will be listed here.

Abstract

Purpose: Whether obesity is an independent risk factor for pulmonary embolism or deep venous thrombosis has not been fully determined.

Methods: We used the database of the National Hospital Discharge Survey to further investigate the potential risk of obesity in venous thromboembolic disease.

Results: The relative risk of deep venous thrombosis, comparing obese patients with non-obese patients, was 2.50 (95% confidence interval [CI] = 2.49-2.51). The relative risk of pulmonary embolism was 2.21 (95% CI = 2.20-2.23). Obese females had a greater relative risk for deep venous thrombosis than obese males, 2.75 (95% CI = 2.74-2.76) versus 2.02 (95% CI = 2.01-2.04). Obesity had the greatest impact on both men and women aged less than 40 years.

Conclusion: The data indicate that obesity is a risk factor for venous thromboembolic disease in men as well as women.

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