Therapeutic Total Plasma Exchange in a Child with Neuroblastoma-related Anti-Hu Syndrome

Overview

Journal Pediatr Nephrol

Specialties Nephrology
Pediatrics

Date 2005 Sep 1

PMID 16133055

Citations 3

Authors

Dannis G van Vuurden

Frans B Plotz

Miranda de Jong

Arend Bokenkamp

Joanna A E van Wijk

Affiliations

Soon will be listed here.

Abstract

A 5-year-old boy underwent total plasma exchange to remove anti-neuronal anti-Hu autoantibodies as a complication of neuroblastoma, leading to autonomic bowel dysfunction. Total plasma exchange (TPE) resulted eventually in a reduction of autoantibody levels, but, more importantly, led to improvement of bowel function. TPE proved to be a safe and effective treatment option in neuroblastoma-related anti-Hu syndrome in a child.

Citing Articles

Anti-Hu antibody associated paraneoplastic neurological syndrome in a child with ganglioneuroblastoma: A rare case report and literature review.

Dai Y, Xiao L, Pan Z, He G, Gao J, Guo X Medicine (Baltimore). 2024; 103(19):e38148.

PMID: 38728479 PMC: 11081564. DOI: 10.1097/MD.0000000000038148.

Comparison of mediastinal and non-mediastinal neuroblastoma and ganglioneuroblastoma associated with opsoclonus-myoclonus syndrome: a systematic review and meta-analysis.

Xie S, Bai C, Li K, Dong K, Yao W Transl Cancer Res. 2022; 11(10):3741-3753.

PMID: 36388023 PMC: 9641106. DOI: 10.21037/tcr-22-1120.

Paraneoplastic neurologic disorders in children.

Wells E, Dalmau J Curr Neurol Neurosci Rep. 2010; 11(2):187-94.

PMID: 21161703 DOI: 10.1007/s11910-010-0169-4.

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