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High Prevalence of Viral Genomes and Inflammation in Peripartum Cardiomyopathy

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Publisher Elsevier
Date 2005 Aug 16
PMID 16098856
Citations 46
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Abstract

Molecular pathologic investigation of endomyocardial biopsy specimens from 26 patients with peripartum cardiomyopathy revealed viral genomes (parvovirus B19, human herpes virus 6, Epstein-Barr virus, and human cytomegalovirus) in 8 patients (30.7%) that were associated immunohistologically with interstitial inflammation. These findings indicate a high prevalence of virus-associated inflammatory changes in peripartum cardiomyopathy.

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