DNA Methyltransferases and Structural-functional Specificity of Eukaryotic DNA Modification

Overview

Journal Biochemistry (Mosc)

Specialty Biochemistry

Date 2005 Aug 16

PMID 16097936

Citations 14

Authors

Ya I Buryanov

T V Shevchuk

Affiliations

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Abstract

Properties of the main families of mammalian, plant, and fungal DNA methyltransferases are considered. Structural-functional specificity of eukaryotic genome sequences methylated by DNA methyltransferases is characterized. The total methylation of cytosine in DNA sequences is described, as well as its relation with RNA interference. Mechanisms of regulation of expression and modulation of DNA methyltransferase activity in the eukaryotic cell are discussed.

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