Postural Imbalance: an Early Sign in HIV-1 Infected Patients

Overview

Journal Eur Arch Psychiatry Clin Neurosci

Specialties Neurology
Psychiatry

Date 1992 Jan 1

PMID 1606190

Citations 8

Authors

C Trenkwalder

A Straube

W Paulus

S Krafczyk

E Schielke

K M Einhaupl

Affiliations

Soon will be listed here.

Abstract

We have recorded postural performance in 50 HIV-infected patients in different stages of the disease (Walter Reed (WR) stages I-VI) by means of a force measuring platform. The results were compared with 50 age-matched controls. A significant instability was particularly evident when standing on an unstable foot support. In patients standing with "eyes closed", postural sway was significantly higher in every patient group (WR I-II: P less than 0.02, WR III-V: P less than 0.001, WR VI: P less than 0.001). Patients in stage WR I-II showed no relevant neurological abnormalities. In agreement with other neurophysiological data in the literature we suggest that postural imbalance could be an early sign of central nervous system penetration of HIV. No correlation with electromyographic or cerebrospinal fluid findings could be found.

Citing Articles

Fall History and Associated Factors Among Adults Living With HIV-1 in the Cape Winelands, South Africa: An Exploratory Investigation.

Berner K, Strijdom H, Essop M, Webster I, Morris L, Louw Q Open Forum Infect Dis. 2019; 6(10):ofz401.

PMID: 31660363 PMC: 6785680. DOI: 10.1093/ofid/ofz401.

Gait and Balance Biomechanics in Older Adults With and Without Human Immunodeficiency Virus.

Ryan A, Roy A, Oursler K AIDS Res Hum Retroviruses. 2019; 35(11-12):1089-1094.

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Investigation of physical and functional impairments experienced by people with active tuberculosis infection: A feasibility pilot study.

van Aswegen H, Roos R, McCree M, Quinn S, Mer M Afr J Disabil. 2019; 8(0):515.

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Variations in plantar pressure and balance in HIV-infected children in antiretroviral therapy.

da Silva Pontes L, Callegari B, Magno L, Moraes A, Silva B, Manso K Sci Rep. 2019; 9(1):4344.

PMID: 30867540 PMC: 6416285. DOI: 10.1038/s41598-019-41028-0.

Objective impairments of gait and balance in adults living with HIV-1 infection: a systematic review and meta-analysis of observational studies.

Berner K, Morris L, Baumeister J, Louw Q BMC Musculoskelet Disord. 2017; 18(1):325.

PMID: 28764704 PMC: 5540197. DOI: 10.1186/s12891-017-1682-2.

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