BiNGO: a Cytoscape Plugin to Assess Overrepresentation of Gene Ontology Categories in Biological Networks

Overview

Journal Bioinformatics

Publisher Oxford University Press

Specialty Biology

Date 2005 Jun 24

PMID 15972284

Citations 2179

Authors

Steven Maere

Karel Heymans

Martin Kuiper

Affiliations

Soon will be listed here.

Abstract

The Biological Networks Gene Ontology tool (BiNGO) is an open-source Java tool to determine which Gene Ontology (GO) terms are significantly overrepresented in a set of genes. BiNGO can be used either on a list of genes, pasted as text, or interactively on subgraphs of biological networks visualized in Cytoscape. BiNGO maps the predominant functional themes of the tested gene set on the GO hierarchy, and takes advantage of Cytoscape's versatile visualization environment to produce an intuitive and customizable visual representation of the results.

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