Chemokines in Tumor Progression and Metastasis

Overview

Journal Cancer Sci

Specialty Oncology

Date 2005 Jun 17

PMID 15958053

Citations 74

Authors

Toshiyuki Tanaka

Zhongbin Bai

Yuttana Srinoulprasert

Bo-Gie Yang

Bogi Yang

Haruko Hayasaka

Masayuki Miyasaka

Affiliations

Soon will be listed here.

Abstract

Although chemokines have been thought of primarily as leukocyte attractants, a growing body of evidence indicates that they also contribute to a number of tumor-related processes, such as tumor cell growth, angiogenesis/angiostasis, local invasion, and metastasis. The current knowledge of the possible involvement of chemokines and their receptors in these cellular events are reviewed here. The operating mechanism of chemokines in relation to metastatic processes in vivo are also discussed.

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